HCG
(Generic name: Human chorionic gonadotropin)
Pregnyl by Organon. 5,000
to 20,000 IU (International Units) per 10 cc vials. This drug is not a steroid
but it is widely used in athletics today. HCG is a natural protein hormone secreted
by the human placenta and purified form the urine of pregnant women. This hormone
is not a natural male hormone but mimics the natural hormone LH (Luetinising Hormone)
almost identically. This LH stimulates the production of testosterone by the testis
in males. Thus HCG sends the same message and results in increased testosterone
production by the testis due to HCGТs effect on the leydig cells of the testis.
Normally this HCG is used to treat women with certain ovarian disorders
and it is used to stimulate the testis of men who may be hypogonadal. Athletes
use HCG to increase the bodyТs own natural production of testosterone which is
often depressed by long term steroid use. Also when steroids are used in high
dosages they can cause false signals to the hypothalamus that results in a depressed
signal to the testicles. Over a period of weeks of this depressed signal the testicles
ability to respond to any signal from the pituitary becomes very weak, which results
in testicular atrophy. To avoid this athletes will use HCG to keep an artificial
signal going to the testis and preventing testicular atrophy. When administered,
HGC raises serum testosterone very quickly. A rise in testosterone firs appears
in about two hours after injecting HCG. The second peak occurs about two to four
days later.
HCG therapy has been found to be very effective in the prevention
of testicular atrophy and to use the bodyТs own biochemical stimulating mechanisms
to increase plasma testosterone level during training. Some steroid users find
that they have some of their best strength and size gains while using HCG in conjunction
with the steroids. This may wee be due to the facts that the body has high level
of natural androgens as well as the artificial steroid hormones at that time.
The optimal dosage for an athlete using HCG has never been established,
but it is thought that a single shot of 1000 to 2000 IU per week will get the
desired results. Cycles on the HCG should be kept down to three weeks at a time
with an off cycle of at least a month in between. For example, one might use the
HCG for two to three weeks in the middle of a cycle, and for two or three weeks
at the end of a cycle. It has been speculated that the prolonged use of HCG could
repress the bodyТs own production of gonadotropins permanently. This is why the
short cycles are the best way to go.
The side effects from HCG use include
gynecomastia, water retention, and an increase in sex drive, mood alterations,
headaches, and high blood pressure. HCG raises androgen levels in males by up
to 400% but it also raises estrogen levels dramatically as well. This is why it
can cause a real case of gynecomastia if dosages get too elevated for that person.
Another side effect seen from HCG use is morning sickness (nausea and vomiting).
There have been no cases of overdose complications with the use of HCG nor have
there been any associated carcinomas, liver or renal impairment. HCG was at one
point looked at to see if it could carry the AIDS virus, due to the fact that
it is biologically active, but the latest word is that this could not be possible
in any way.
So we see how HCG be used by athletes to avoid some of the
problems associated with abruptly stopping a steroid cycle. This product is also
not picked up on steroid tests, so some athletes use it to keep androgen levels
high before a contest that has drug testing. HCG must be refergerated after it
is mixed together, and it then has a life of about 10 weeks. It is taken intramuscularly
only; this drug is often available by order of a physician if you show symptoms
of hypogonadism. It is hard to find on the black market.
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